Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism

Targeting the ubiquitin proteasome pathway has emerged as a rational approach in the treatment of human cancers. Autophagy has been described as a cytoprotective mechanism to increase tumor cell survival under stress conditions. Here, we have focused on the role of proteasome inhibition in cell cycl...

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Detalles Bibliográficos
Autores principales: Gavilán, Elena, Giráldez, Servando, Sánchez-Aguayo, Inmaculada, Romero, Francisco, Ruano, Diego, Daza, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419540/
https://www.ncbi.nlm.nih.gov/pubmed/25941117
http://dx.doi.org/10.1038/srep10027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419540/
https://www.ncbi.nlm.nih.gov/pubmed/25941117
http://dx.doi.org/10.1038/srep10027

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