Cargando…

Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism

Targeting the ubiquitin proteasome pathway has emerged as a rational approach in the treatment of human cancers. Autophagy has been described as a cytoprotective mechanism to increase tumor cell survival under stress conditions. Here, we have focused on the role of proteasome inhibition in cell cycl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gavilán, Elena, Giráldez, Servando, Sánchez-Aguayo, Inmaculada, Romero, Francisco, Ruano, Diego, Daza, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419540/ https://www.ncbi.nlm.nih.gov/pubmed/25941117 http://dx.doi.org/10.1038/srep10027

Ejemplares similares

GSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition
por: Gavilán, E, et al.
Publicado: (2013)

Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line
por: Ali, Norlaily Mohd, et al.
Publicado: (2016)

Ophiobolin O Isolated from Aspergillus ustus Induces G1 Arrest of MCF-7 Cells through Interaction with AKT/GSK3β/Cyclin D1 Signaling
por: Lv, Cuiting, et al.
Publicado: (2015)

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus
por: Pintado, Cristina, et al.
Publicado: (2012)

Synthesis of an anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell line
por: Yeap, SweeKeong, et al.
Publicado: (2015)

A partnership with the proteasome; the destructive nature of GSK3
por: Robertson, Holly, et al.
Publicado: (2018)

YSY01A, a Novel Proteasome Inhibitor, Induces Cell Cycle Arrest on G2 Phase in MCF-7 Cells via ERα and PI3K/Akt Pathways
por: Xue, Bingjie, et al.
Publicado: (2015)

Farnesiferol C induces cell cycle arrest and apoptosis mediated by oxidative stress in MCF-7 cell line
por: Hasanzadeh, Davoud, et al.
Publicado: (2017)

Need an EGO to escape arrest
por: LeBrasseur, Nicole
Publicado: (2005)

Peptide SA12 inhibits proliferation of breast cancer cell lines MCF-7 and MDA-MB-231 through G0/G1 phase cell cycle arrest
por: Yang, Longfei, et al.
Publicado: (2018)

Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3
por: Boulpicante, Mathilde, et al.
Publicado: (2020)

Eco-Friendly Formulated Zinc Oxide Nanoparticles: Induction of Cell Cycle Arrest and Apoptosis in the MCF-7 Cancer Cell Line
por: Boroumand Moghaddam, Amin, et al.
Publicado: (2017)

Inhibitory effect of isoamericanol A from Jatropha curcas seeds on the growth of MCF-7 human breast cancer cell line by G2/M cell cycle arrest
por: Katagi, Ayako, et al.
Publicado: (2016)

Dillenia Suffruticosa Extract Inhibits Proliferation of Human Breast Cancer Cell Lines (MCF-7 and MDA-MB-231) via Induction of G(2)/M Arrest and Apoptosis
por: Armania, Nurdin, et al.
Publicado: (2013)

DNA damage induced by oridonin involves cell cycle arrest at G2/M phase in human MCF-7 cells
por: Zhang, Tao, et al.
Publicado: (2013)

CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope
por: Cardinaud, Sylvain, et al.
Publicado: (2011)

An Antioxidant Extract of Tropical Lichen,Parmotrema reticulatum, Induces Cell Cycle Arrest and Apoptosis in Breast Carcinoma Cell Line MCF-7
por: Ghate, Nikhil Baban, et al.
Publicado: (2013)

DNA-damage and cell cycle arrest initiated anti-cancer potency of super tiny carbon dots on MCF7 cell line
por: Şimşek, Sinem, et al.
Publicado: (2020)

Cell cycle arrest and apoptotic studies of Terminalia chebula against MCF-7 breast cancer cell line: an in vitro and in silico approach
por: Reddy, Pruthvish, et al.
Publicado: (2023)

Effects of an Anticarcinogenic Bowman-Birk Protease Inhibitor on Purified 20S Proteasome and MCF-7 Breast Cancer Cells
por: Souza, Larissa da Costa, et al.
Publicado: (2014)

All-trans retinoic acid (ATRA)-induced apoptosis is preceded by G1 arrest in human MCF-7 breast cancer cells.
por: Mangiarotti, R., et al.
Publicado: (1998)

Quercetin Arrests in G2 phase, Upregulates INXS LncRNA and Downregulates UCA1 LncRNA in MCF-7 Cells
por: Rezaie, Fatemeh, et al.
Publicado: (2021)

Cytotoxicity Enhancement of Paclitaxel by Loading on Stearate-g-dextran Micelles on Breast Cancer Cell Line MCF-7
por: Ghaffari, Fatemeh, et al.
Publicado: (2018)

Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182(R)-6
por: Jensen, B L, et al.
Publicado: (1999)

Escape from G1 arrest during acute MEK inhibition drives the acquisition of drug resistance
por: Channathodiyil, Prasanna, et al.
Publicado: (2022)

Rad23 escapes degradation because it lacks a proteasome initiation region
por: Fishbain, Susan, et al.
Publicado: (2011)

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope
por: Textor, Ana, et al.
Publicado: (2016)

Proteasomal Processing Immune Escape Mechanisms in Platinum-Treated Advanced Bladder Cancer
por: Wessolly, Michael, et al.
Publicado: (2022)

Dendrobium candidum inhibits MCF-7 cells proliferation by inducing cell cycle arrest at G2/M phase and regulating key biomarkers
por: Sun, Jing, et al.
Publicado: (2015)

Cytotoxicity and Genotoxicity Assessment of Sandalwood Essential Oil in Human Breast Cell Lines MCF-7 and MCF-10A
por: Ortiz, Carmen, et al.
Publicado: (2016)

SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability
por: Giráldez, Servando, et al.
Publicado: (2014)

Cellular Toxicity of Nanogenomedicine in MCF-7 Cell Line: MTT assay
por: Ahmadian, Somaieh, et al.
Publicado: (2009)

BAG5 regulates PTEN stability in MCF-7 cell line
por: Ying, Zhang, et al.
Publicado: (2013)

Antiproliferative effect of dexamethasone in the MCF-7 breast cancer cell line
por: BUXANT, FREDERIC, et al.
Publicado: (2015)

Oxidants-Antioxidants Profile in the Breast Cancer Cell Line MCF-7
por: Isnaini, Isnaini, et al.
Publicado: (2018)

GSK3β Regulates Differentiation and Growth Arrest in Glioblastoma
por: Korur, Serdar, et al.
Publicado: (2009)

Effects of 8-hydroxyquinoline-coated graphene oxide on cell death and apoptosis in MCF-7 and MCF-10 breast cell lines
por: Kheiltash, Firoozeh, et al.
Publicado: (2020)

Comparison of Anticancer Activity of Dorycnium pentaphyllum Extract on MCF-7 and MCF-12A Cell Line: Correlation with Invasion and Adhesion
por: Koygun, Gözde, et al.
Publicado: (2021)

Proteins from Lignosus tigris with selective apoptotic cytotoxicity towards MCF7 cell line and suppresses MCF7-xenograft tumor growth
por: Kong, Boon Hong, et al.
Publicado: (2020)

Correction: Preventing tumor escape by targeting a post-proteasomal trimming independent epitope
por: Textor, Ana, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dip8kl6kadmijqud23pptffhp9