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3D Structural Fluctuation of IgG1 Antibody Revealed by Individual Particle Electron Tomography
Commonly used methods for determining protein structure, including X-ray crystallography and single-particle reconstruction, often provide a single and unique three-dimensional (3D) structure. However, in these methods, the protein dynamics and flexibility/fluctuation remain mostly unknown. Here, we...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419541/ https://www.ncbi.nlm.nih.gov/pubmed/25940394 http://dx.doi.org/10.1038/srep09803 |