Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines

The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an S(N)2-type ring opening followed by cyclization of the...

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Detalles Bibliográficos
Autores principales: Sun, Hongnan, Huang, Binbin, Lin, Run, Yang, Chao, Xia, Wujiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419545/
https://www.ncbi.nlm.nih.gov/pubmed/25977727
http://dx.doi.org/10.3762/bjoc.11.59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419545/
https://www.ncbi.nlm.nih.gov/pubmed/25977727
http://dx.doi.org/10.3762/bjoc.11.59

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