Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides

A novel and simple strategy for the efficient synthesis of the corresponding tetrahydroquinolines from N,N-dimethylanilines and maleimides using visible light in an air atmosphere in the presence of Eosin Y as a photocatalyst has been developed. The metal-free protocol involves aerobic oxidative cyc...

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Autores principales: Liang, Zhongwei, Xu, Song, Tian, Wenyan, Zhang, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419562/
https://www.ncbi.nlm.nih.gov/pubmed/25977716
http://dx.doi.org/10.3762/bjoc.11.48
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author Liang, Zhongwei
Xu, Song
Tian, Wenyan
Zhang, Ronghua
author_facet Liang, Zhongwei
Xu, Song
Tian, Wenyan
Zhang, Ronghua
author_sort Liang, Zhongwei
collection PubMed
description A novel and simple strategy for the efficient synthesis of the corresponding tetrahydroquinolines from N,N-dimethylanilines and maleimides using visible light in an air atmosphere in the presence of Eosin Y as a photocatalyst has been developed. The metal-free protocol involves aerobic oxidative cyclization via sp(3) C–H bond functionalization process to afford good yields in a one-pot procedure under mild conditions.
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spelling pubmed-44195622015-05-14 Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides Liang, Zhongwei Xu, Song Tian, Wenyan Zhang, Ronghua Beilstein J Org Chem Full Research Paper A novel and simple strategy for the efficient synthesis of the corresponding tetrahydroquinolines from N,N-dimethylanilines and maleimides using visible light in an air atmosphere in the presence of Eosin Y as a photocatalyst has been developed. The metal-free protocol involves aerobic oxidative cyclization via sp(3) C–H bond functionalization process to afford good yields in a one-pot procedure under mild conditions. Beilstein-Institut 2015-04-01 /pmc/articles/PMC4419562/ /pubmed/25977716 http://dx.doi.org/10.3762/bjoc.11.48 Text en Copyright © 2015, Liang et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Liang, Zhongwei
Xu, Song
Tian, Wenyan
Zhang, Ronghua
Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides
title Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides
title_full Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides
title_fullStr Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides
title_full_unstemmed Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides
title_short Eosin Y-catalyzed visible-light-mediated aerobic oxidative cyclization of N,N-dimethylanilines with maleimides
title_sort eosin y-catalyzed visible-light-mediated aerobic oxidative cyclization of n,n-dimethylanilines with maleimides
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419562/
https://www.ncbi.nlm.nih.gov/pubmed/25977716
http://dx.doi.org/10.3762/bjoc.11.48
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