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Janus kinase inhibitors: jackpot or potluck?

The reports of a unique mutation in the Janus kinase-2 gene (JAK2) in polycythemia vera by several independent groups in 2005 quickly spurred the development of the Janus kinase inhibitors. In one of the great victories of translational research in recent times, the first smallmolecule Janus kinase...

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Detalles Bibliográficos
Autores principales: Pavithran, Keechilat, Pande, Shripad Brahmanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419642/
https://www.ncbi.nlm.nih.gov/pubmed/25992203
http://dx.doi.org/10.4081/oncol.2012.e13