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Interaction between therapeutic interventions for Alzheimer’s disease and physiological Aβ clearance mechanisms

Most therapeutic agents are designed to target a molecule or pathway without consideration of the mechanisms involved in the physiological turnover or removal of that target. In light of this and in particular for Alzheimer’s disease, a number of therapeutic interventions are presently being develop...

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Detalles Bibliográficos
Autores principales: Morrone, Christopher D., Liu, Mingzhe, Black, Sandra E., McLaurin, JoAnne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419721/
https://www.ncbi.nlm.nih.gov/pubmed/25999850
http://dx.doi.org/10.3389/fnagi.2015.00064