Increased Expression of X-Linked Genes in Mammals Is Associated with a Higher Stability of Transcripts and an Increased Ribosome Density

Mammalian sex chromosomes evolved from the degeneration of one homolog of a pair of ancestral autosomes, the proto-Y. This resulted in a gene dose imbalance that is believed to be restored (partially or fully) through upregulation of gene expression from the single active X-chromosome in both sexes...

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Detalles Bibliográficos
Autores principales: Faucillion, Marie-Line, Larsson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419800/
https://www.ncbi.nlm.nih.gov/pubmed/25786432
http://dx.doi.org/10.1093/gbe/evv054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419800/
https://www.ncbi.nlm.nih.gov/pubmed/25786432
http://dx.doi.org/10.1093/gbe/evv054

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