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Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance

Antimicrobial chemotherapy is critical in the fight against infectious diseases caused by Entamoeba histolytica. Among the drugs available for the treatment of amebiasis, metronidazole (MTZ) is considered the drug of choice. Recently, in vitro studies have described MTZ resistance and the potential...

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Detalles Bibliográficos
Autores principales: Penuliar, Gil M., Nakada-Tsukui, Kumiko, Nozaki, Tomoyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419850/
https://www.ncbi.nlm.nih.gov/pubmed/25999919
http://dx.doi.org/10.3389/fmicb.2015.00354