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How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario

Alzheimer’s disease (AD) is the most common neurodegenerative disorder and is characterized by progressive memory loss and cognitive decline. One of the hallmarks of AD is the overproduction of amyloid-beta aggregates that range from the toxic soluble oligomer (Aβo) form to extracellular accumulatio...

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Detalles Bibliográficos
Autores principales: Arrázola, Macarena S., Silva-Alvarez, Carmen, Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419851/
https://www.ncbi.nlm.nih.gov/pubmed/25999816
http://dx.doi.org/10.3389/fncel.2015.00166