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Recent advances toward a molecular mechanism of efflux pump inhibition

Multidrug resistance (MDR) in Gram-negative pathogens, such as the Enterobacteriaceae and Pseudomonas aeruginosa, poses a significant threat to our ability to effectively treat infections caused by these organisms. A major component in the development of the MDR phenotype in Gram-negative bacteria i...

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Detalles Bibliográficos
Autores principales: Opperman, Timothy J., Nguyen, Son T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419859/
https://www.ncbi.nlm.nih.gov/pubmed/25999939
http://dx.doi.org/10.3389/fmicb.2015.00421