Crystal structure of 4-bromo-2-[(E)-N-(2,2,6,6-tetra­methyl­piperidin-4-yl)carboximido­yl]phenol dihydrate

In the title hydrate, C(16)H(23)BrN(2)O·2H(2)O, the organic mol­ecule features a strong intra­molecular O—H⋯N hydrogen bond. The piperidine ring, in addition, adopts a chair conformation with the exocyclic C—N bond in an equatorial orientation. The water molecules of crystallization are disordered (...

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Detalles Bibliográficos
Autores principales: Mague, Joel T., Mohamed, Shaaban K., Akkurt, Mehmet, Abdelhamid, Antar A., Albayati, Mustafa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420100/
https://www.ncbi.nlm.nih.gov/pubmed/25995942
http://dx.doi.org/10.1107/S2056989015007471
Descripción
Sumario:In the title hydrate, C(16)H(23)BrN(2)O·2H(2)O, the organic mol­ecule features a strong intra­molecular O—H⋯N hydrogen bond. The piperidine ring, in addition, adopts a chair conformation with the exocyclic C—N bond in an equatorial orientation. The water molecules of crystallization are disordered (each over two sets of sites with half occupancy. In the crystal, they associate into corrugated (100) sheets of (H(2)O)(4) tetra­mers linked by O—H⋯O hydrogen bonds. The organic mol­ecules, in turn, are arranged at both sides of these sheets, linked by water–piperidine O—H⋯N hydrogen bonds.