Immobilization of Zidovudine Derivatives on the SBA-15 Mesoporous Silica and Evaluation of Their Cytotoxic Activity

Novel zidovudine derivatives, able to be covalently conjugated to silica surface, have been obtained and grafted to SBA-15 mesoporous silica. Cytotoxic activity of the hybrid organic-inorganic (zidovudine derivatives-silica) systems against HeLa and KB cell lines has been analyzed. Addition of folic...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewandowski, Dawid, Lewandowska, Marta, Ruszkowski, Piotr, Pińska, Anita, Schroeder, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420263/
https://www.ncbi.nlm.nih.gov/pubmed/25942021
http://dx.doi.org/10.1371/journal.pone.0126251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420263/
https://www.ncbi.nlm.nih.gov/pubmed/25942021
http://dx.doi.org/10.1371/journal.pone.0126251

Ejemplares similares