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Immobilization of Zidovudine Derivatives on the SBA-15 Mesoporous Silica and Evaluation of Their Cytotoxic Activity

Novel zidovudine derivatives, able to be covalently conjugated to silica surface, have been obtained and grafted to SBA-15 mesoporous silica. Cytotoxic activity of the hybrid organic-inorganic (zidovudine derivatives-silica) systems against HeLa and KB cell lines has been analyzed. Addition of folic...

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Detalles Bibliográficos
Autores principales:	Lewandowski, Dawid, Lewandowska, Marta, Ruszkowski, Piotr, Pińska, Anita, Schroeder, Grzegorz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420263/ https://www.ncbi.nlm.nih.gov/pubmed/25942021 http://dx.doi.org/10.1371/journal.pone.0126251

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