Parathyroid Hormone Induces Bone Cell Motility and Loss of Mature Osteocyte Phenotype through L-Calcium Channel Dependent and Independent Mechanisms

Parathyroid Hormone (PTH) can exert both anabolic and catabolic effects on the skeleton, potentially through expression of the PTH type1 receptor (PTH1R), which is highly expressed in osteocytes. To determine the cellular and molecular mechanisms responsible, we examined the effects of PTH on osteob...

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Detalles Bibliográficos
Autores principales: Prideaux, Matthew, Dallas, Sarah L., Zhao, Ning, Johnsrud, Erica D., Veno, Patricia A., Guo, Dayong, Mishina, Yuji, Harris, Stephen E., Bonewald, Lynda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420268/
https://www.ncbi.nlm.nih.gov/pubmed/25942444
http://dx.doi.org/10.1371/journal.pone.0125731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420268/
https://www.ncbi.nlm.nih.gov/pubmed/25942444
http://dx.doi.org/10.1371/journal.pone.0125731

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