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Persistence of the Recombinant Genomes of Woodchuck Hepatitis Virus in the Mouse Model

Hydrodynamic injection (HI) with a replication competent hepatitis B virus (HBV) genome may lead to transient or prolonged HBV replication in mice. However, the prolonged HBV persistence after HI depends on the specific backbone of the vector carrying HBV genome and the genetic background of the mou...

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Detalles Bibliográficos
Autores principales: Pan, Danzhen, Lin, Yong, Wu, Weimin, Song, Jingjiao, Zhang, Ejuan, Wu, Chunchen, Chen, Xinwen, Hu, Kanghong, Yang, Dongliang, Xu, Yang, Lu, Mengji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420481/
https://www.ncbi.nlm.nih.gov/pubmed/25942393
http://dx.doi.org/10.1371/journal.pone.0125658