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Persistence of the Recombinant Genomes of Woodchuck Hepatitis Virus in the Mouse Model
Hydrodynamic injection (HI) with a replication competent hepatitis B virus (HBV) genome may lead to transient or prolonged HBV replication in mice. However, the prolonged HBV persistence after HI depends on the specific backbone of the vector carrying HBV genome and the genetic background of the mou...
Autores principales: | Pan, Danzhen, Lin, Yong, Wu, Weimin, Song, Jingjiao, Zhang, Ejuan, Wu, Chunchen, Chen, Xinwen, Hu, Kanghong, Yang, Dongliang, Xu, Yang, Lu, Mengji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420481/ https://www.ncbi.nlm.nih.gov/pubmed/25942393 http://dx.doi.org/10.1371/journal.pone.0125658 |
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