Regulating the Coordination State of a Heme Protein by a Designed Distal Hydrogen-Bonding Network

Heme coordination state determines the functional diversity of heme proteins. Using myoglobin as a model protein, we designed a distal hydrogen-bonding network by introducing both distal glutamic acid (Glu29) and histidine (His43) residues and regulated the heme into a bis-His coordination state wit...

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Detalles Bibliográficos
Autores principales: Du, Jun-Fang, Li, Wei, Li, Lianzhi, Wen, Ge-Bo, Lin, Ying-Wu, Tan, Xiangshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420578/
https://www.ncbi.nlm.nih.gov/pubmed/25969804
http://dx.doi.org/10.1002/open.201402108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420578/
https://www.ncbi.nlm.nih.gov/pubmed/25969804
http://dx.doi.org/10.1002/open.201402108

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