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Targeting lung cancer stem-like cells with TRAIL gene armed oncolytic adenovirus

Lung cancer stem cell (LCSC) is critical in cancer initiation, progression, drug resistance and relapse. Disadvantages showed in conventional lung cancer therapy probably because of its existence. In this study, lung cancer cell line A549 cells propagated as spheroid bodies (named as A549 sphere cel...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Xu, Haineng, Huang, Weidan, Ding, Miao, Xiao, Jing, Yang, Dongmei, Li, Huaguang, Liu, Xin-Yuan, Chu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420595/
https://www.ncbi.nlm.nih.gov/pubmed/25683371
http://dx.doi.org/10.1111/jcmm.12397