TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea

Toll-like receptor-3 (TLR3) and RNA helicase retinoic-acid-inducible protein-1 (RIG-I) serve as cytoplasmic sensors for viral RNA components. In this study, we investigated how the TLR3 and RIG-I signalling pathway was stimulated by viral infection to produce interleukin (IL)-32-mediated pro-inflamm...

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Detalles Bibliográficos
Autores principales: Park, Ga Bin, Hur, Dae Young, Kim, Yeong Seok, Lee, Hyun-Kyung, Yang, Jae Wook, Kim, Daejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420606/
https://www.ncbi.nlm.nih.gov/pubmed/25754842
http://dx.doi.org/10.1111/jcmm.12495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420606/
https://www.ncbi.nlm.nih.gov/pubmed/25754842
http://dx.doi.org/10.1111/jcmm.12495

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