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A novel leptin antagonist peptide inhibits breast cancer growth in vitro and in vivo

The role of the obesity cytokine leptin in breast cancer progression has raised interest in interfering with leptin's actions as a valuable therapeutic strategy. Leptin interacts with its receptor through three different binding sites: I–III. Site I is crucial for the formation of an active lep...

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Detalles Bibliográficos
Autores principales: Catalano, Stefania, Leggio, Antonella, Barone, Ines, De Marco, Rosaria, Gelsomino, Luca, Campana, Antonella, Malivindi, Rocco, Panza, Salvatore, Giordano, Cinzia, Liguori, Alessia, Bonofiglio, Daniela, Liguori, Angelo, Andò, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420614/
https://www.ncbi.nlm.nih.gov/pubmed/25721149
http://dx.doi.org/10.1111/jcmm.12517