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A novel leptin antagonist peptide inhibits breast cancer growth in vitro and in vivo
The role of the obesity cytokine leptin in breast cancer progression has raised interest in interfering with leptin's actions as a valuable therapeutic strategy. Leptin interacts with its receptor through three different binding sites: I–III. Site I is crucial for the formation of an active lep...
Autores principales: | Catalano, Stefania, Leggio, Antonella, Barone, Ines, De Marco, Rosaria, Gelsomino, Luca, Campana, Antonella, Malivindi, Rocco, Panza, Salvatore, Giordano, Cinzia, Liguori, Alessia, Bonofiglio, Daniela, Liguori, Angelo, Andò, Sebastiano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420614/ https://www.ncbi.nlm.nih.gov/pubmed/25721149 http://dx.doi.org/10.1111/jcmm.12517 |
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