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Causal inference methods to assess safety upper bounds in randomized trials with noncompliance

BACKGROUND: Premature discontinuation and other forms of noncompliance with treatment assignment can complicate causal inference of treatment effects in randomized trials. The intent-to-treat analysis gives unbiased estimates for causal effects of treatment assignment on outcome, but may understate...

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Detalles Bibliográficos
Autores principales: Wang, Yiting, Berlin, Jesse A, Pinheiro, José, Wilcox, Marsha A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420771/
https://www.ncbi.nlm.nih.gov/pubmed/25733675
http://dx.doi.org/10.1177/1740774515572352