Mice lacking neutral amino acid transporter B(0)AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control

OBJECTIVE: Type 2 diabetes arises from insulin resistance of peripheral tissues followed by dysfunction of β-cells in the pancreas due to metabolic stress. Both depletion and supplementation of neutral amino acids have been discussed as strategies to improve insulin sensitivity. Here we characterise...

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Detalles Bibliográficos
Autores principales: Jiang, Yang, Rose, Adam J., Sijmonsma, Tjeerd P., Bröer, Angelika, Pfenninger, Anja, Herzig, Stephan, Schmoll, Dieter, Bröer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421019/
https://www.ncbi.nlm.nih.gov/pubmed/25973388
http://dx.doi.org/10.1016/j.molmet.2015.02.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421019/
https://www.ncbi.nlm.nih.gov/pubmed/25973388
http://dx.doi.org/10.1016/j.molmet.2015.02.003

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