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Metabolomics Profiling to Investigate the Pharmacologic Mechanisms of Berberine for the Treatment of High-Fat Diet-Induced Nonalcoholic Steatohepatitis

Objective. Berberine has been used to treat nonalcoholic steatohepatitis (NASH), which has been addressed in many studies. In this study, we investigated the molecular pharmacology mechanisms of berberine using metabolomic techniques. Methods. Sprague-Dawley rats were randomly divided into three gro...

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Detalles Bibliográficos
Autores principales: Li, Jian, Liu, Zezhou, Guo, Mingxing, Xu, Kejia, Jiang, Miao, Lu, Aiping, Gao, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421035/
https://www.ncbi.nlm.nih.gov/pubmed/25977701
http://dx.doi.org/10.1155/2015/897914