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De novo lipogenesis in metabolic homeostasis: More friend than foe?

BACKGROUND: An acute surplus of carbohydrates, and other substrates, can be converted and safely stored as lipids in adipocytes via de novo lipogenesis (DNL). However, in obesity, a condition characterized by chronic positive energy balance, DNL in non-adipose tissues may lead to ectopic lipid accum...

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Detalles Bibliográficos
Autores principales: Solinas, Giovanni, Borén, Jan, Dulloo, Abdul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421107/
https://www.ncbi.nlm.nih.gov/pubmed/25973385
http://dx.doi.org/10.1016/j.molmet.2015.03.004