Novel solid phase-based ELISA assays contribute to an improved detection of anti-HLA antibodies and to an increased reliability of pre- and post-transplant crossmatching

Antibodies directed against HLA antigens of a given organ donor represent the dominating reason for hyper-acute or acute allograft rejections. In order to select recipients without donor-specific antibodies, a standard crossmatch (CM) procedure, the complement-dependent cytotoxicity assay (CDC), was...

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Detalles Bibliográficos
Autores principales: Schlaf, Gerald, Pollok-Kopp, Beatrix, Manzke, Till, Schurat, Oliver, Altermann, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
In-Depth Clinical Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421419/
https://www.ncbi.nlm.nih.gov/pubmed/25949460
http://dx.doi.org/10.1093/ndtplus/sfq156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421419/
https://www.ncbi.nlm.nih.gov/pubmed/25949460
http://dx.doi.org/10.1093/ndtplus/sfq156

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