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Novel solid phase-based ELISA assays contribute to an improved detection of anti-HLA antibodies and to an increased reliability of pre- and post-transplant crossmatching
Antibodies directed against HLA antigens of a given organ donor represent the dominating reason for hyper-acute or acute allograft rejections. In order to select recipients without donor-specific antibodies, a standard crossmatch (CM) procedure, the complement-dependent cytotoxicity assay (CDC), was...
Autores principales: | Schlaf, Gerald, Pollok-Kopp, Beatrix, Manzke, Till, Schurat, Oliver, Altermann, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421419/ https://www.ncbi.nlm.nih.gov/pubmed/25949460 http://dx.doi.org/10.1093/ndtplus/sfq156 |
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