E2F1-Mediated FOS Induction in Arsenic Trioxide–Induced Cellular Transformation: Effects of Global H3K9 Hypoacetylation and Promoter-Specific Hyperacetylation in Vitro

Background: Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood. Objective: We investigated the impact of tolerated and toxic arsen...

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Detalles Bibliográficos
Autores principales: Rahman, Sunniyat, Housein, Zjwan, Dabrowska, Aleksandra, Mayán, Maria Dolores, Boobis, Alan R., Hajji, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421767/
https://www.ncbi.nlm.nih.gov/pubmed/25574600
http://dx.doi.org/10.1289/ehp.1408302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421767/
https://www.ncbi.nlm.nih.gov/pubmed/25574600
http://dx.doi.org/10.1289/ehp.1408302

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