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E2F1-Mediated FOS Induction in Arsenic Trioxide–Induced Cellular Transformation: Effects of Global H3K9 Hypoacetylation and Promoter-Specific Hyperacetylation in Vitro
Background: Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood. Objective: We investigated the impact of tolerated and toxic arsen...
Autores principales: | Rahman, Sunniyat, Housein, Zjwan, Dabrowska, Aleksandra, Mayán, Maria Dolores, Boobis, Alan R., Hajji, Nabil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
NLM-Export
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421767/ https://www.ncbi.nlm.nih.gov/pubmed/25574600 http://dx.doi.org/10.1289/ehp.1408302 |
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