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1Differential immune mechanism to HIV-1 Tat variants and its regulation by AEA

In the retina, Müller glia is a dominant player of immune response. The HIV-1 transactivator viral protein (Tat) induces production of several neurotoxic cytokines in retinal cells. We show that HIV-1 clades Tat B and C act differentially on Müller glia, which is reflected in apoptosis, activation o...

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Detalles Bibliográficos
Autores principales: Krishnan, Gopinath, Chatterjee, Nivedita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421801/
https://www.ncbi.nlm.nih.gov/pubmed/25943894
http://dx.doi.org/10.1038/srep09887