Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors

REarranged during Transfection (RET) is a transmembrane receptor tyrosine kinase required for normal development and maintenance of neurons of the central and peripheral nervous systems. Deregulation of RET and hyperactivity of the RET kinase is intimately connected to several types of human cancers...

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Detalles Bibliográficos
Autores principales: Ferreira, Rubén, Nilsson, Jesper R., Solano, Carlos, Andréasson, Joakim, Grøtli, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421829/
https://www.ncbi.nlm.nih.gov/pubmed/25944708
http://dx.doi.org/10.1038/srep09769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421829/
https://www.ncbi.nlm.nih.gov/pubmed/25944708
http://dx.doi.org/10.1038/srep09769

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