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Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein
Helicobacter pylori cagA-positive strain delivers the CagA oncoprotein into gastric epithelial cells and at the same time elicits stomach inflammation. To experimentally investigate the pathophysiological interplay between CagA and inflammation, transgenic mice systemically expressing the bacterial...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421872/ https://www.ncbi.nlm.nih.gov/pubmed/25944120 http://dx.doi.org/10.1038/srep10024 |