Modular Synthesis of Heparin-Related Tetra-, Hexa- and Octasaccharides with Differential O-6 Protections: Programming for Regiodefined 6-O-Modifications

Heparin and heparan sulphate (H/HS) are important members of the glycosaminoglycan family of sugars that regulate a substantial number of biological processes. Such biological promiscuity is underpinned by hetereogeneity in their molecular structure. The degree of O-sulfation, particularly at the 6-...

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Detalles Bibliográficos
Autores principales: Baráth, Marek, Hansen, Steen U., Dalton, Charlotte E., Jayson, Gordon C., Miller, Gavin J., Gardiner, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421873/
https://www.ncbi.nlm.nih.gov/pubmed/25859776
http://dx.doi.org/10.3390/molecules20046167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421873/
https://www.ncbi.nlm.nih.gov/pubmed/25859776
http://dx.doi.org/10.3390/molecules20046167

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