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Modular Synthesis of Heparin-Related Tetra-, Hexa- and Octasaccharides with Differential O-6 Protections: Programming for Regiodefined 6-O-Modifications

Heparin and heparan sulphate (H/HS) are important members of the glycosaminoglycan family of sugars that regulate a substantial number of biological processes. Such biological promiscuity is underpinned by hetereogeneity in their molecular structure. The degree of O-sulfation, particularly at the 6-...

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Detalles Bibliográficos
Autores principales:	Baráth, Marek, Hansen, Steen U., Dalton, Charlotte E., Jayson, Gordon C., Miller, Gavin J., Gardiner, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421873/ https://www.ncbi.nlm.nih.gov/pubmed/25859776 http://dx.doi.org/10.3390/molecules20046167

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