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Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients

BACKGROUND: As IL-12 and IL-18 have important immunostimulatory role the aim of this study was to investigate their in vitro effects on functional and receptor characteristics of NK cells and their subsets in healthy controls (HC) and metastatic melanoma patients (MM). METHODS: Peripheral blood mono...

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Detalles Bibliográficos
Autores principales: Mirjačić Martinović, Katarina, Babović, Nada, Džodić, Radan, Jurišić, Vladimir, Matković, Suzana, Konjević, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421987/
https://www.ncbi.nlm.nih.gov/pubmed/25889680
http://dx.doi.org/10.1186/s12967-015-0479-z