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Increased efficiency of Campylobacter jejuni N-oligosaccharyltransferase PglB by structure-guided engineering

Conjugate vaccines belong to the most efficient preventive measures against life-threatening bacterial infections. Functional expression of N-oligosaccharyltransferase (N-OST) PglB of Campylobacter jejuni in Escherichia coli enables a simplified production of glycoconjugate vaccines in prokaryotic c...

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Detalles Bibliográficos
Autores principales: Ihssen, Julian, Haas, Jürgen, Kowarik, Michael, Wiesli, Luzia, Wacker, Michael, Schwede, Torsten, Thöny-Meyer, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422122/
https://www.ncbi.nlm.nih.gov/pubmed/25833378
http://dx.doi.org/10.1098/rsob.140227