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Increased efficiency of Campylobacter jejuni N-oligosaccharyltransferase PglB by structure-guided engineering
Conjugate vaccines belong to the most efficient preventive measures against life-threatening bacterial infections. Functional expression of N-oligosaccharyltransferase (N-OST) PglB of Campylobacter jejuni in Escherichia coli enables a simplified production of glycoconjugate vaccines in prokaryotic c...
Autores principales: | Ihssen, Julian, Haas, Jürgen, Kowarik, Michael, Wiesli, Luzia, Wacker, Michael, Schwede, Torsten, Thöny-Meyer, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422122/ https://www.ncbi.nlm.nih.gov/pubmed/25833378 http://dx.doi.org/10.1098/rsob.140227 |
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