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Balanced splicing at the Tat-specific HIV-1 3′ss A3 is critical for HIV-1 replication
BACKGROUND: The viral regulatory protein Tat is essential for establishing a productive transcription from the 5′-LTR promoter during the early phase of viral gene expression. Formation of the Tat-encoding mRNAs requires splicing at the viral 3′ss A3, which has previously been shown to be both negat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422144/ https://www.ncbi.nlm.nih.gov/pubmed/25889056 http://dx.doi.org/10.1186/s12977-015-0154-8 |