Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease

BACKGROUND: Neks, mammalian orthologs of the fungal protein kinase never-in-mitosis A, have been implicated in the pathogenesis of polycystic kidney disease. Among them, Nek1 is the primary protein inactivated in kat2J mouse models of PKD. RESULT: We report the expression pattern of Nek1 and charact...

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Detalles Bibliográficos
Autores principales: Chen, Yumay, Chiang, Huai-Chin, Litchfield, Patricia, Pena, Michelle, Juang, Charity, Riley, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422189/
https://www.ncbi.nlm.nih.gov/pubmed/25030234
http://dx.doi.org/10.1186/s12929-014-0063-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422189/
https://www.ncbi.nlm.nih.gov/pubmed/25030234
http://dx.doi.org/10.1186/s12929-014-0063-5

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