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Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation

BACKGROUND: Noopept (N-phenyl-acetyl-L-prolylglycine ethyl ester) was constructed as a dipeptide analog of the standard cognition enhancer, piracetam. Our previous experiments have demonstrated the cognition restoring effect of noopept in several animal models of Alzheimer disease (AD). Noopept was...

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Detalles Bibliográficos
Autores principales: Ostrovskaya, Rita U, Vakhitova, Yulia V, Kuzmina, Uliyana Sh, Salimgareeva, Milyausha Kh, Zainullina, Liana F, Gudasheva, Tatiana A, Vakhitov, Vener A, Seredenin, Sergey B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422191/
https://www.ncbi.nlm.nih.gov/pubmed/25096780
http://dx.doi.org/10.1186/s12929-014-0074-2