Pinocembrin suppresses TGF-β1-induced epithelial-mesenchymal transition and metastasis of human Y-79 retinoblastoma cells through inactivating αvβ3 integrin/FAK/p38α signaling pathway

BACKGROUND: Pinocembrin is the most abundant flavonoid in propolis. In this study, we investigated the antimetastatic effect of pinocembrin on TGF-β1-induced epithelial-mesenchymal transition (EMT) and metastasis of human Y-79 retinoblastoma cells. RESULTS: Firstly, the results showed that pinocembr...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Kun-Shiang, Shi, Ming-Der, Chien, Chi-Sheng, Shih, Yuan-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422197/
https://www.ncbi.nlm.nih.gov/pubmed/25949790
http://dx.doi.org/10.1186/2045-3701-4-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422197/
https://www.ncbi.nlm.nih.gov/pubmed/25949790
http://dx.doi.org/10.1186/2045-3701-4-41

Ejemplares similares