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Pinocembrin suppresses TGF-β1-induced epithelial-mesenchymal transition and metastasis of human Y-79 retinoblastoma cells through inactivating αvβ3 integrin/FAK/p38α signaling pathway

BACKGROUND: Pinocembrin is the most abundant flavonoid in propolis. In this study, we investigated the antimetastatic effect of pinocembrin on TGF-β1-induced epithelial-mesenchymal transition (EMT) and metastasis of human Y-79 retinoblastoma cells. RESULTS: Firstly, the results showed that pinocembr...

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Detalles Bibliográficos
Autores principales:	Chen, Kun-Shiang, Shi, Ming-Der, Chien, Chi-Sheng, Shih, Yuan-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422197/ https://www.ncbi.nlm.nih.gov/pubmed/25949790 http://dx.doi.org/10.1186/2045-3701-4-41

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