Perturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human disease

Ribosomal RNA (rRNA) gene (rDNA) transcription by RNA Polymerase I (Pol I) drives cell growth and underlies nucleolar structure and function, indirectly coordinating many fundamental cellular processes. The importance of keeping rDNA transcription under tight control is reflected by the fact that de...

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Detalles Bibliográficos
Autores principales: Diesch, Jeannine, Hannan, Ross D, Sanij, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422213/
https://www.ncbi.nlm.nih.gov/pubmed/25949792
http://dx.doi.org/10.1186/2045-3701-4-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422213/
https://www.ncbi.nlm.nih.gov/pubmed/25949792
http://dx.doi.org/10.1186/2045-3701-4-43

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