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Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids

BACKGROUND: The complex cellular networks within tumors, the cytokine milieu, and tumor immune escape mechanisms affecting infiltration and anti-tumor activity of immune cells are of great interest to understand tumor formation and to decipher novel access points for cancer therapy. However, cellula...

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Detalles Bibliográficos
Autores principales: Giannattasio, Ariane, Weil, Sandra, Kloess, Stephan, Ansari, Nariman, Stelzer, Ernst H K, Cerwenka, Adelheid, Steinle, Alexander, Koehl, Ulrike, Koch, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422268/
https://www.ncbi.nlm.nih.gov/pubmed/25933805
http://dx.doi.org/10.1186/s12885-015-1321-y