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Keap1 expression has independent prognostic value in pancreatic adenocarcinomas

BACKGROUND: Oxidative stress and redox-regulating enzymes may potentially accelerate pancreatic carcinogenesis and also affect chemoresistance. Recently major antioxidant response regulator NF-E2-related factor 2 (Nrf2) has been linked to poor prognosis in pancreatic cancer. Nrf2 activity is strictl...

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Detalles Bibliográficos
Autores principales:	Isohookana, Joel, Haapasaari, Kirsi-Maria, Soini, Ylermi, Karihtala, Peeter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422296/ https://www.ncbi.nlm.nih.gov/pubmed/25879528 http://dx.doi.org/10.1186/s13000-015-0258-4

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