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Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer

BACKGROUND: Chimeric read-through RNAs are transcripts originating from two directly adjacent genes (<10 kb) on the same DNA strand. Although they are found in next-generation whole transcriptome sequencing (RNA-Seq) data on a regular basis, investigating them further has usually been refrained f...

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Detalles Bibliográficos
Autores principales: Pflueger, Dorothee, Mittmann, Christiane, Dehler, Silvia, Rubin, Mark A, Moch, Holger, Schraml, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422297/
https://www.ncbi.nlm.nih.gov/pubmed/25888189
http://dx.doi.org/10.1186/s12864-015-1446-z