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Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells

BACKGROUND: Platelet-derived growth factor-BB (PDGF-BB) has been implicated in the proliferation, migration and synthetic activities of smooth muscle cells that characterize physiologic and pathologic tissue remodeling in hollow organs. However, neither the molecular basis of PDGFR-regulated signali...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Ramachandran, Aruna, You, Sungyong, Jeong, HyoBin, Morley, Samantha, Mulone, Michelle D, Logvinenko, Tanya, Kim, Jayoung, Hwang, Daehee, Freeman, Michael R, Adam, Rosalyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422302/
https://www.ncbi.nlm.nih.gov/pubmed/25080971
http://dx.doi.org/10.1186/s12964-014-0044-z