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Human endogenous retroviruses sustain complex and cooperative regulation of gene-containing loci and unannotated megabase-sized regions

BACKGROUND: Evidence suggests that some human endogenous retroviruses and endogenous retrovirus-like repeats (here collectively ERVs) regulate the expression of neighboring genes in normal and disease states; e.g. the human globin locus is regulated by an ERV9 that coordinates long-range gene switch...

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Detalles Bibliográficos
Autores principales: Sokol, Martin, Jessen, Karen Margrethe, Pedersen, Finn Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422309/
https://www.ncbi.nlm.nih.gov/pubmed/25927889
http://dx.doi.org/10.1186/s12977-015-0161-9