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A reporter mouse for optical imaging of inflammation in mdx muscles

BACKGROUND: Duchenne muscular dystrophy (DMD) is due to mutations in the gene coding for human DMD; DMD is characterized by progressive muscle degeneration, inflammation, fat accumulation, and fibrosis. The mdx mouse model of DMD lacks dystrophin protein and undergoes a predictable disease course. W...

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Detalles Bibliográficos
Autores principales: Martinez, Leonel, Ermolova, Natalia V, Ishikawa, Tomo-O, Stout, David B, Herschman, Harvey R, Spencer, Melissa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422315/
https://www.ncbi.nlm.nih.gov/pubmed/25949789
http://dx.doi.org/10.1186/s13395-015-0042-x